Regulations of the Act provide clear and comprehensive instructions on how confirmation of patient death should be confirmed. This includes a cerebral angiography of the brain – this is an X-ray that shows that there is no longer a blood supply a to the brain. The brain is then said to be irreparably damaged (also known as brain death). When all requirements are met, a death certificated is issued and signed by two doctors. At this point, death is determined as certain.